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Filopodial retraction force is generated by cortical actin dynamics and controlled by reversible tethering at the tip

Filopodia are dynamic, finger-like plasma membrane protrusions that sense the mechanical and chemical surroundings of the cell. Here, we show in epithelial cells that the dynamics of filopodial extension and retraction are determined by the difference between the actin polymerization rate at the tip...

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Hlavní autoři: Bornschlögl, Thomas, Romero, Stéphane, Vestergaard, Christian L., Joanny, Jean-François, Van Nhieu, Guy Tran, Bassereau, Patricia
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3839779/
https://ncbi.nlm.nih.gov/pubmed/24198333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1316572110
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