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Dynamic filopodial forces induce accumulation, damage, and plastic remodeling of 3D extracellular matrices

The mechanical properties of the extracellular matrix (ECM)–a complex, 3D, fibrillar scaffold of cells in physiological environments–modulate cell behavior and can drive tissue morphogenesis, regeneration, and disease progression. For simplicity, it is often convenient to assume these properties to...

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Veröffentlicht in:PLoS Comput Biol
Hauptverfasser: Malandrino, Andrea, Trepat, Xavier, Kamm, Roger D., Mak, Michael
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6472805/
https://ncbi.nlm.nih.gov/pubmed/30958816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006684
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