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Dynamic tensile forces drive collective cell migration through three-dimensional extracellular matrices

Collective cell migration drives tissue remodeling during development, wound repair, and metastatic invasion. The physical mechanisms by which cells move cohesively through dense three-dimensional (3D) extracellular matrix (ECM) remain incompletely understood. Here, we show directly that migration o...

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Publicado en:Sci Rep
Autores principales: Gjorevski, Nikolce, S. Piotrowski, Alexandra, Varner, Victor D., Nelson, Celeste M.
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4499882/
https://ncbi.nlm.nih.gov/pubmed/26165921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep11458
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