BRD9 binds cell type-specific chromatin regions regulating leukemic cell survival via STAT5 inhibition

Leukemia is characterized by genetic and epigenetic mutations resulting in selection of cancer cells, which are unable to differentiate. Although genetic alterations are difficult to target, the epigenome is intrinsically dynamic and readily offers new therapeutic strategies. Thus, identifying cance...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Death Dis
Prif Awduron: Del Gaudio, Nunzio, Di Costanzo, Antonella, Liu, Ning Qing, Conte, Lidio, Migliaccio, Antimo, Vermeulen, Michiel, Martens, Joost H. A., Stunnenberg, Hendrik G., Nebbioso, Angela, Altucci, Lucia
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2019
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6472371/
https://ncbi.nlm.nih.gov/pubmed/31000698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1570-9
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg