BRD9 binds cell type-specific chromatin regions regulating leukemic cell survival via STAT5 inhibition

Leukemia is characterized by genetic and epigenetic mutations resulting in selection of cancer cells, which are unable to differentiate. Although genetic alterations are difficult to target, the epigenome is intrinsically dynamic and readily offers new therapeutic strategies. Thus, identifying cance...

Full description

Saved in:
Bibliographic Details
Published in:Cell Death Dis
Main Authors: Del Gaudio, Nunzio, Di Costanzo, Antonella, Liu, Ning Qing, Conte, Lidio, Migliaccio, Antimo, Vermeulen, Michiel, Martens, Joost H. A., Stunnenberg, Hendrik G., Nebbioso, Angela, Altucci, Lucia
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2019
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6472371/
https://ncbi.nlm.nih.gov/pubmed/31000698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1570-9
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items