BRD9 binds cell type-specific chromatin regions regulating leukemic cell survival via STAT5 inhibition

Leukemia is characterized by genetic and epigenetic mutations resulting in selection of cancer cells, which are unable to differentiate. Although genetic alterations are difficult to target, the epigenome is intrinsically dynamic and readily offers new therapeutic strategies. Thus, identifying cance...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Del Gaudio, Nunzio, Di Costanzo, Antonella, Liu, Ning Qing, Conte, Lidio, Migliaccio, Antimo, Vermeulen, Michiel, Martens, Joost H. A., Stunnenberg, Hendrik G., Nebbioso, Angela, Altucci, Lucia
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6472371/
https://ncbi.nlm.nih.gov/pubmed/31000698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1570-9
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