S1PR2 antagonist ameliorate high glucose-induced fission and dysfunction of mitochondria in HRGECs via regulating ROCK1

AIMS: Sphingosine-1-phosphate receptor 2 (S1PR2) is a G-protein-coupled receptor that regulates sphingosine-1-phosphate-triggered cellular response. However, the role of S1PR2 in diabetes-induced glomerular endothelial cell dysfunction remains unclear. This study aims to investigate the effect of S1...

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Detalhes bibliográficos
Publicado no:BMC Nephrol
Main Authors: Chen, Wei, Xiang, Hong, Chen, Ruifang, Yang, Jie, Yang, Xiaoping, Zhou, Jianda, Liu, Hengdao, Zhao, Shaoli, Xiao, Jie, Chen, Pan, Chen, Alex F., Chen, Shuhua, Lu, Hongwei
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6471837/
https://ncbi.nlm.nih.gov/pubmed/30999892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12882-019-1323-0
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