Targeting prokineticin system counteracts hypersensitivity, neuroinflammation, and tissue damage in a mouse model of bortezomib-induced peripheral neuropathy

BACKGROUND: Neuropathy is a dose-limiting side effect of many chemotherapeutics, including bortezomib. The mechanisms underlying this condition are not fully elucidated even if a contribution of neuroinflammation was suggested. Here, we investigated the role of a chemokine family, the prokineticins...

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Vydáno v:J Neuroinflammation
Hlavní autoři: Moschetti, Giorgia, Amodeo, Giada, Maftei, Daniela, Lattanzi, Roberta, Procacci, Patrizia, Sartori, Patrizia, Balboni, Gianfranco, Onnis, Valentina, Conte, Vincenzo, Panerai, Alberto, Sacerdote, Paola, Franchi, Silvia
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2019
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6471808/
https://ncbi.nlm.nih.gov/pubmed/30995914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-019-1461-0
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