Prokineticin Receptor Inhibition With PC1 Protects Mouse Primary Sensory Neurons From Neurotoxic Effects of Chemotherapeutic Drugs in vitro

Neurotoxicity is a common side effect of chemotherapeutics that often leads to the development of chemotherapy-induced peripheral neuropathy (CIPN). The peptide Prokineticin 2 (PK2) has a key role in experimental models of CIPN and can be considered an insult-inducible endangering mediator. Since pr...

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Udgivet i:Front Immunol
Main Authors: Moschetti, Giorgia, Kalpachidou, Theodora, Amodeo, Giada, Lattanzi, Roberta, Sacerdote, Paola, Kress, Michaela, Franchi, Silvia
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7541916/
https://ncbi.nlm.nih.gov/pubmed/33072073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.02119
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