Antagonism of the Prokineticin System Prevents and Reverses Allodynia and Inflammation in a Mouse Model of Diabetes

Neuropathic pain is a severe diabetes complication and its treatment is not satisfactory. It is associated with neuroinflammation-related events that participate in pain generation and chronicization. Prokineticins are a new family of chemokines that has emerged as critical players in immune system,...

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Pubblicato in:PLoS One
Autori principali: Castelli, Mara, Amodeo, Giada, Negri, Lucia, Lattanzi, Roberta, Maftei, Daniela, Gotti, Cecilia, Pistillo, Francesco, Onnis, Valentina, Congu, Cenzo, Panerai, Alberto E., Sacerdote, Paola, Franchi, Silvia
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2016
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4701417/
https://ncbi.nlm.nih.gov/pubmed/26730729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0146259
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