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Oxidation of KCNB1 potassium channels in the murine brain during aging is associated with cognitive impairment
Voltage-gated potassium (K(+)) channel sub-family B member 1 (KCNB1, Kv2.1) is known to undergo oxidation-induced oligomerization during aging but whether this process affects brain’s physiology was not known. Here, we used 10, 16 and 22 month-old transgenic mice overexpressing a KCNB1 variant that...
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| Pubblicato in: | Biochem Biophys Res Commun |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6471606/ https://ncbi.nlm.nih.gov/pubmed/30922570 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2019.03.130 |
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