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Characterization of the High-Affinity Drug Ligand Binding Site of Mouse Recombinant TSPO

The optimization of translocator protein (TSPO) ligands for Positron Emission Tomography as well as for the modulation of neurosteroids is a critical necessity for the development of TSPO-based diagnostics and therapeutics of neuropsychiatrics and neurodegenerative disorders. Structural hints on the...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Iatmanen-Harbi, Soria, Senicourt, lucile, Papadopoulos, Vassilios, Lequin, Olivier, Lacapere, Jean-Jacques
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6470738/
https://ncbi.nlm.nih.gov/pubmed/30901938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20061444
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