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Mitochondrial TSPO Deficiency Triggers Retrograde Signaling in MA-10 Mouse Tumor Leydig Cells

The mitochondrial translocator protein (TSPO) has been shown to bind cholesterol with high affinity and is involved in mediating its availability for steroidogenesis. We recently reported that targeted Tspo gene deletion in MA-10 mouse tumor Leydig cells resulted in reduced cAMP-stimulated steroid f...

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Bibliografske podrobnosti
izdano v:Int J Mol Sci
Main Authors: Fan, Jinjiang, Papadopoulos, Vassilios
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7795497/
https://ncbi.nlm.nih.gov/pubmed/33383772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22010252
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