Binding Affinity of Some Endogenous and Synthetic TSPO Ligands Regarding the rs6971 Polymorphism

An intriguing target involved in several pathophysiological processes is the 18 kDa translocator protein (TSPO), of which exact functions remained elusive until now. A single nucleotide polymorphism in the TSPO gene influences the binding affinity of endogenous and synthetic TSPO ligands by facilita...

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Bibliographic Details
Published in:Int J Mol Sci
Main Authors: Berroterán-Infante, Neydher, Tadić, Monika, Hacker, Marcus, Wadsak, Wolfgang, Mitterhauser, Markus
Format: Artigo
Language:Inglês
Published: MDPI 2019
Subjects:
Communication
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6387295/
https://ncbi.nlm.nih.gov/pubmed/30699908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20030563
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