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Secondary nucleation and elongation occur at different sites on Alzheimer’s amyloid-β aggregates
The aggregates of the Aβ peptide associated with Alzheimer’s disease are able to both grow in size as well as generate, through secondary nucleation, new small oligomeric species, that are major cytotoxins associated with neuronal death. Despite the importance of these amyloid fibril-dependent proce...
में बचाया:
| में प्रकाशित: | Sci Adv |
|---|---|
| मुख्य लेखकों: | , , , , , , , , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
American Association for the Advancement of Science
2019
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6469941/ https://ncbi.nlm.nih.gov/pubmed/31001578 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aau3112 |
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