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The APOE Gene is Differentially Methylated in Alzheimer’s Disease

The ε4 allele of the human apolipoprotein E gene (APOE) is a well-proven genetic risk factor for the late onset form of Alzheimer’s disease (AD). However, the biological mechanisms through which the ε4 allele contributes to disease pathophysiology are incompletely understood. The three common allele...

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Detalles Bibliográficos
Publicado en:J Alzheimers Dis
Main Authors: Foraker, Jessica, Millard, Steven P., Leong, Lesley, Thomson, Zachary, Chen, Sunny, Keene, C. Dirk, Bekris, Lynn M., Yu, Chang-En
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6469491/
https://ncbi.nlm.nih.gov/pubmed/26402071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-143060
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