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The APOE Gene is Differentially Methylated in Alzheimer’s Disease

The ε4 allele of the human apolipoprotein E gene (APOE) is a well-proven genetic risk factor for the late onset form of Alzheimer’s disease (AD). However, the biological mechanisms through which the ε4 allele contributes to disease pathophysiology are incompletely understood. The three common allele...

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Dettagli Bibliografici
Pubblicato in:J Alzheimers Dis
Autori principali: Foraker, Jessica, Millard, Steven P., Leong, Lesley, Thomson, Zachary, Chen, Sunny, Keene, C. Dirk, Bekris, Lynn M., Yu, Chang-En
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6469491/
https://ncbi.nlm.nih.gov/pubmed/26402071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-143060
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