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The APOE Gene is Differentially Methylated in Alzheimer’s Disease

The ε4 allele of the human apolipoprotein E gene (APOE) is a well-proven genetic risk factor for the late onset form of Alzheimer’s disease (AD). However, the biological mechanisms through which the ε4 allele contributes to disease pathophysiology are incompletely understood. The three common allele...

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Detalhes bibliográficos
Publicado no:J Alzheimers Dis
Main Authors: Foraker, Jessica, Millard, Steven P., Leong, Lesley, Thomson, Zachary, Chen, Sunny, Keene, C. Dirk, Bekris, Lynn M., Yu, Chang-En
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6469491/
https://ncbi.nlm.nih.gov/pubmed/26402071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-143060
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