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Alpha6-Integrin Regulates FGFR1 Expression through the ZEB1/YAP1 Transcription Complex in Glioblastoma Stem Cells Resulting in Enhanced Proliferation and Stemness

Glioblastoma (GBM) is the most lethal primary brain tumor in adults and is known to be particularly aggressive and resistant to anti-cancer therapies, mainly due to the presence of GBM stem cells (GBMSC). By in vitro approaches supported by analysis from patients’ databases, we determined how α6-int...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Cancers (Basel)
Main Authors: KOWALSKI-CHAUVEL, Aline, GOUAZE-ANDERSSON, Valerie, BARICAULT, Laurent, MARTIN, Elodie, DELMAS, Caroline, TOULAS, Christine, COHEN-JONATHAN-MOYAL, Elizabeth, SEVA, Catherine
פורמט: Artigo
שפה:Inglês
יצא לאור: MDPI 2019
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6468800/
https://ncbi.nlm.nih.gov/pubmed/30909436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11030406
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