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Alpha6-Integrin Regulates FGFR1 Expression through the ZEB1/YAP1 Transcription Complex in Glioblastoma Stem Cells Resulting in Enhanced Proliferation and Stemness

Glioblastoma (GBM) is the most lethal primary brain tumor in adults and is known to be particularly aggressive and resistant to anti-cancer therapies, mainly due to the presence of GBM stem cells (GBMSC). By in vitro approaches supported by analysis from patients’ databases, we determined how α6-int...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: KOWALSKI-CHAUVEL, Aline, GOUAZE-ANDERSSON, Valerie, BARICAULT, Laurent, MARTIN, Elodie, DELMAS, Caroline, TOULAS, Christine, COHEN-JONATHAN-MOYAL, Elizabeth, SEVA, Catherine
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6468800/
https://ncbi.nlm.nih.gov/pubmed/30909436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11030406
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