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Targeting progastrin enhances radiosensitization of colorectal cancer cells

A high percentage of advanced rectal cancers are resistant to radiation. Therefore, increasing the efficacy of radiotherapy by targeting factors involved in radioresistance seems to be an attractive strategy. Here we demonstrated that the pro-hormone progastrin (PG), known to be over-expressed in CR...

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Bibliografske podrobnosti
izdano v:Oncotarget
Main Authors: Kowalski-Chauvel, Aline, Gouaze-Andersson, Valerie, Vignolle-Vidoni, Alix, Delmas, Caroline, Toulas, Christine, Cohen-Jonathan-Moyal, Elizabeth, Seva, Catherine
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5601677/
https://ncbi.nlm.nih.gov/pubmed/28938581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17274
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