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Normalizing HDAC2 Levels in the Spinal Cord Alleviates Thermal and Mechanical Hyperalgesia After Peripheral Nerve Injury and Promotes GAD65 and KCC2 Expression

Neuropathic pain is a worldwide health concern with poor treatment outcomes. Accumulating evidence suggests that histone hypoacetylation is involved in development and maintenance of neuropathic pain. Thus, many natural and synthetic histone deacetylase (HDACs) inhibitors were tested and exhibited a...

詳細記述

保存先:
書誌詳細
出版年:Front Neurosci
主要な著者: Ouyang, Bihan, Chen, Dan, Hou, Xinran, Wang, Tongxuan, Wang, Jian, Zou, Wangyuan, Song, Zongbin, Huang, Changsheng, Guo, Qulian, Weng, Yingqi
フォーマット: Artigo
言語:Inglês
出版事項: Frontiers Media S.A. 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6468568/
https://ncbi.nlm.nih.gov/pubmed/31024248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2019.00346
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