GPER Mediates a Feedforward FGF2/FGFR1 Paracrine Activation Coupling CAFs to Cancer Cells toward Breast Tumor Progression

The FGF2/FGFR1 paracrine loop is involved in the cross-talk between breast cancer cells and components of the tumor stroma as cancer-associated fibroblasts (CAFs). By quantitative PCR (qPCR), western blot, immunofluorescence analysis, ELISA and ChIP assays, we demonstrated that 17β-estradiol (E2) an...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Cells
Autors principals: Santolla, Maria Francesca, Vivacqua, Adele, Lappano, Rosamaria, Rigiracciolo, Damiano Cosimo, Cirillo, Francesca, Galli, Giulia Raffaella, Talia, Marianna, Brunetti, Giuseppe, Miglietta, Anna Maria, Belfiore, Antonino, Maggiolini, Marcello
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2019
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6468560/
https://ncbi.nlm.nih.gov/pubmed/30866584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8030223
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars