Focal adhesion kinase (FAK) activation by estrogens involves GPER in triple-negative breast cancer cells

BACKGROUND: Focal adhesion kinase (FAK) is a cytoplasmatic protein tyrosine kinase that associates with both integrins and growth factor receptors toward the adhesion, migration and invasion of cancer cells. The G-protein coupled estrogen receptor (GPER) has been involved in the stimulatory action o...

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Detalhes bibliográficos
Publicado no:J Exp Clin Cancer Res
Main Authors: Rigiracciolo, Damiano Cosimo, Santolla, Maria Francesca, Lappano, Rosamaria, Vivacqua, Adele, Cirillo, Francesca, Galli, Giulia Raffaella, Talia, Marianna, Muglia, Lucia, Pellegrino, Michele, Nohata, Nijiro, Di Martino, Maria Teresa, Maggiolini, Marcello
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6364402/
https://ncbi.nlm.nih.gov/pubmed/30728047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1056-8
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