IGF-1/IGF-1R/FAK/YAP Transduction Signaling Prompts Growth Effects in Triple-Negative Breast Cancer (TNBC) Cells

Triple-negative breast cancer (TNBC) is an aggressive breast tumor subtype that currently lacks targeted treatment options. The role played by the insulin-like growth factor-1 (IGF-1) and its cognate receptor IGF-1R in TNBC has been reported. Nevertheless, the molecular mechanisms by which the IGF-1...

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Publicado en:Cells
Main Authors: Rigiracciolo, Damiano Cosimo, Nohata, Nijiro, Lappano, Rosamaria, Cirillo, Francesca, Talia, Marianna, Scordamaglia, Domenica, Gutkind, J. Silvio, Maggiolini, Marcello
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2020
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7225986/
https://ncbi.nlm.nih.gov/pubmed/32325700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9041010
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