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A multi-axial RNA joint with a large range of motion promotes sampling of an active ribozyme conformation
Investigating the dynamics of structural elements in functional RNAs is important to better understand their mechanism and for engineering RNAs with novel functions. Previously, we performed rational engineering studies with the Varkud satellite (VS) ribozyme and switched its specificity toward non-...
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| Pubblicato in: | Nucleic Acids Res |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6468304/ https://ncbi.nlm.nih.gov/pubmed/30993347 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz098 |
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