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A multi-axial RNA joint with a large range of motion promotes sampling of an active ribozyme conformation
Investigating the dynamics of structural elements in functional RNAs is important to better understand their mechanism and for engineering RNAs with novel functions. Previously, we performed rational engineering studies with the Varkud satellite (VS) ribozyme and switched its specificity toward non-...
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| Publicado en: | Nucleic Acids Res |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6468304/ https://ncbi.nlm.nih.gov/pubmed/30993347 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz098 |
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