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Role of SLV in SLI substrate recognition by the Neurospora VS ribozyme

Substrate recognition by the VS ribozyme involves a magnesium-dependent loop/loop interaction between the SLI substrate and the SLV hairpin from the catalytic domain. Recent NMR studies of SLV demonstrated that magnesium ions stabilize a U-turn loop structure and trigger a conformational change for...

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Detalhes bibliográficos
Main Authors: Bouchard, Patricia, Lacroix-Labonté, Julie, Desjardins, Geneviève, Lampron, Philipe, Lisi, Véronique, Lemieux, Sébastien, Major, François, Legault, Pascale
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2271362/
https://ncbi.nlm.nih.gov/pubmed/18314503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.824308
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