Human H4 tail stimulates HIV-1 integration through binding to the carboxy-terminal domain of integrase

The integration of the retroviral genome into the chromatin of the infected cell is catalysed by the integrase (IN)•viral DNA complex (intasome). This process requires functional association between the integration complex and the nucleosomes. Direct intasome/histone contacts have been reported to m...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Mauro, Eric, Lesbats, Paul, Lapaillerie, Delphine, Chaignepain, Stephane, Maillot, Benoit, Oladosu, Oyindamola, Robert, Xavier, Fiorini, Francesca, Kieffer, Bruno, Bouaziz, Serge, Gouet, Patrice, Ruff, Marc, Parissi, Vincent
Format: Artigo
Language:Inglês
Published: Oxford University Press 2019
Subjects:
Nucleic Acid Enzymes
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6468294/
https://ncbi.nlm.nih.gov/pubmed/30767014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz091
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