Human H4 tail stimulates HIV-1 integration through binding to the carboxy-terminal domain of integrase

The integration of the retroviral genome into the chromatin of the infected cell is catalysed by the integrase (IN)•viral DNA complex (intasome). This process requires functional association between the integration complex and the nucleosomes. Direct intasome/histone contacts have been reported to m...

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Vydáno v:Nucleic Acids Res
Hlavní autoři: Mauro, Eric, Lesbats, Paul, Lapaillerie, Delphine, Chaignepain, Stephane, Maillot, Benoit, Oladosu, Oyindamola, Robert, Xavier, Fiorini, Francesca, Kieffer, Bruno, Bouaziz, Serge, Gouet, Patrice, Ruff, Marc, Parissi, Vincent
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2019
Témata:
Nucleic Acid Enzymes
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6468294/
https://ncbi.nlm.nih.gov/pubmed/30767014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz091
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