Mitochondrial RNA granules are critically dependent on mtDNA replication factors Twinkle and mtSSB

Newly synthesized mitochondrial RNA is concentrated in structures juxtaposed to nucleoids, called RNA granules, that have been implicated in mitochondrial RNA processing and ribosome biogenesis. Here we show that two classical mtDNA replication factors, the mtDNA helicase Twinkle and single-stranded...

Full description

Saved in:
Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Hensen, Fenna, Potter, Alisa, van Esveld, Selma L, Tarrés-Solé, Aleix, Chakraborty, Arka, Solà, Maria, Spelbrink, Johannes N
Format: Artigo
Language:Inglês
Published: Oxford University Press 2019
Subjects:
RNA and RNA-protein complexes
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6468249/
https://ncbi.nlm.nih.gov/pubmed/30715486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz047
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items