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Mitochondrial RNA granules are critically dependent on mtDNA replication factors Twinkle and mtSSB

Newly synthesized mitochondrial RNA is concentrated in structures juxtaposed to nucleoids, called RNA granules, that have been implicated in mitochondrial RNA processing and ribosome biogenesis. Here we show that two classical mtDNA replication factors, the mtDNA helicase Twinkle and single-stranded...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Hensen, Fenna, Potter, Alisa, van Esveld, Selma L, Tarrés-Solé, Aleix, Chakraborty, Arka, Solà, Maria, Spelbrink, Johannes N
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6468249/
https://ncbi.nlm.nih.gov/pubmed/30715486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz047
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