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Regulation of Myelination by Exosome Associated Retinoic Acid Release from NG2-Positive Cells

In the CNS, oligodendrocytes are responsible for myelin formation and maintenance. Following spinal cord injury, oligodendrocyte loss and an inhibitory milieu compromise remyelination and recovery. Here, we explored the role of retinoic acid receptor-beta (RARβ) signaling in remyelination. Using a m...

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Bibliographic Details
Published in:J Neurosci
Main Authors: Goncalves, Maria B., Wu, Yue, Clarke, Earl, Grist, John, Hobbs, Carl, Trigo, Diogo, Jack, Julian, Corcoran, Jonathan P.T.
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6468108/
https://ncbi.nlm.nih.gov/pubmed/30760627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2922-18.2019
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