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Bioproduction of pure, kilobase-scale single-stranded DNA

Scalable production of kilobase single-stranded DNA (ssDNA) with sequence control has applications in therapeutics, gene synthesis and sequencing, scaffolded DNA origami, and archival DNA memory storage. Biological production of circular ssDNA (cssDNA) using M13 addresses these needs at low cost. Ho...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Shepherd, Tyson R., Du, Rebecca R., Huang, Hellen, Wamhoff, Eike-Christian, Bathe, Mark
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6467869/
https://ncbi.nlm.nih.gov/pubmed/30992517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-42665-1
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