Role of nanoscale antigen organization on B-cell activation probed using DNA origami

Vaccine efficacy can be increased by arraying immunogens in multivalent form on virus-like nanoparticles to enhance B cell activation. However, the effects of antigen copy number, spacing, and affinity, as well as the dimensionality and rigidity of scaffold presentation on B cell activation remain p...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:Nat Nanotechnol
Huvudupphovsmän: Veneziano, Rémi, Moyer, Tyson J., Stone, Matthew B., Wamhoff, Eike-Christian, Read, Benjamin J., Mukherjee, Sayak, Shepherd, Tyson R., Das, Jayajit, Schief, William R., Irvine, Darrell J., Bathe, Mark
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2020
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7415668/
https://ncbi.nlm.nih.gov/pubmed/32601450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41565-020-0719-0
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk