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Predicting double-strand DNA breaks using epigenome marks or DNA at kilobase resolution
Double-strand breaks (DSBs) result from the attack of both DNA strands by multiple sources, including radiation and chemicals. DSBs can cause the abnormal chromosomal rearrangements associated with cancer. Recent techniques allow the genome-wide mapping of DSBs at high resolution, enabling the compr...
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| Udgivet i: | Genome Biol |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5856001/ https://ncbi.nlm.nih.gov/pubmed/29544533 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-018-1411-7 |
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