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Predicting double-strand DNA breaks using epigenome marks or DNA at kilobase resolution

Double-strand breaks (DSBs) result from the attack of both DNA strands by multiple sources, including radiation and chemicals. DSBs can cause the abnormal chromosomal rearrangements associated with cancer. Recent techniques allow the genome-wide mapping of DSBs at high resolution, enabling the compr...

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Bibliografische gegevens
Gepubliceerd in:Genome Biol
Hoofdauteurs: Mourad, Raphaël, Ginalski, Krzysztof, Legube, Gaëlle, Cuvier, Olivier
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2018
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5856001/
https://ncbi.nlm.nih.gov/pubmed/29544533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-018-1411-7
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