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Predicting double-strand DNA breaks using epigenome marks or DNA at kilobase resolution

Double-strand breaks (DSBs) result from the attack of both DNA strands by multiple sources, including radiation and chemicals. DSBs can cause the abnormal chromosomal rearrangements associated with cancer. Recent techniques allow the genome-wide mapping of DSBs at high resolution, enabling the compr...

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Bibliografiske detaljer
Udgivet i:Genome Biol
Main Authors: Mourad, Raphaël, Ginalski, Krzysztof, Legube, Gaëlle, Cuvier, Olivier
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5856001/
https://ncbi.nlm.nih.gov/pubmed/29544533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-018-1411-7
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