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An Efficient Method for Labeling Single Domain Antibody Fragments with (18)F Using Tetrazine-Trans-Cyclooctene Ligation and a Renal Brush Border Enzyme-Cleavable Linker
Single domain antibody fragments (sdAbs) labeled with (18)F have shown promise for assessing the status of oncological targets such as the human epidermal growth factor receptor 2 (HER2) by positron emission tomography (PET). Earlier, we evaluated two residualizing prosthetic agents for (18)F-labeli...
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| Veröffentlicht in: | Bioconjug Chem |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6467799/ https://ncbi.nlm.nih.gov/pubmed/30384599 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.bioconjchem.8b00699 |
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