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Synthesis and in vitro characterization of trehalose-based inhibitors of mycobacterial trehalose 6-phosphate phosphatases
α,α’-Trehalose plays roles in the synthesis of several cell wall components involved in pathogenic mycobacteria virulence. Its absence in mammalian biochemistry makes trehalose-related biochemical processes potential targets for chemotherapy. The trehalose-6-phosphate synthase (TPS)/trehalose-6-phos...
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| Publicado no: | Chembiochem |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6467533/ https://ncbi.nlm.nih.gov/pubmed/30402996 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201800551 |
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