Enzyme characteristics of pathogen-specific trehalose-6-phosphate phosphatases

Owing to the key role of trehalose in pathogenic organisms, there has recently been growing interest in trehalose metabolism for therapeutic purposes. Trehalose-6-phosphate phosphatase (TPP) is a pivotal enzyme in the most prominent biosynthesis pathway (OtsAB). Here, we compare the enzyme character...

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Udgivet i:Sci Rep
Main Authors: Cross, Megan, Rajan, Siji, Chekaiban, Janine, Saunders, Jake, Hamilton, Chloe, Kim, Jeong-Sun, Coster, Mark J., Gasser, Robin B., Hofmann, Andreas
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5435700/
https://ncbi.nlm.nih.gov/pubmed/28515463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-02220-2
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