Discovery and validation of a prognostic proteomic signature for tuberculosis progression: A prospective cohort study

BACKGROUND: A nonsputum blood test capable of predicting progression of healthy individuals to active tuberculosis (TB) before clinical symptoms manifest would allow targeted treatment to curb transmission. We aimed to develop a proteomic biomarker of risk of TB progression for ultimate translation...

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Detalhes bibliográficos
Publicado no:PLoS Med
Main Authors: Penn-Nicholson, Adam, Hraha, Thomas, Thompson, Ethan G., Sterling, David, Mbandi, Stanley Kimbung, Wall, Kirsten M., Fisher, Michelle, Suliman, Sara, Shankar, Smitha, Hanekom, Willem A., Janjic, Nebojsa, Hatherill, Mark, Kaufmann, Stefan H. E., Sutherland, Jayne, Walzl, Gerhard, De Groote, Mary Ann, Ochsner, Urs, Zak, Daniel E., Scriba, Thomas J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6467365/
https://ncbi.nlm.nih.gov/pubmed/30990820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.1002781
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