Discovery and Validation of a Six-Marker Serum Protein Signature for the Diagnosis of Active Pulmonary Tuberculosis

New non-sputum biomarker tests for active tuberculosis (TB) diagnostics are of the highest priority for global TB control. We performed in-depth proteomic analysis using the 4,000-plex SOMAscan assay on 1,470 serum samples from seven countries where TB is endemic. All samples were from patients with...

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Detalhes bibliográficos
Publicado no:J Clin Microbiol
Main Authors: De Groote, Mary A., Sterling, David G., Hraha, Thomas, Russell, Theresa M., Green, Louis S., Wall, Kirsten, Kraemer, Stephan, Ostroff, Rachel, Janjic, Nebojsa, Ochsner, Urs A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Mycobacteriology and Aerobic Actinomycetes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5625392/
https://ncbi.nlm.nih.gov/pubmed/28794177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.00467-17
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