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Discovery and validation of a prognostic proteomic signature for tuberculosis progression: A prospective cohort study

BACKGROUND: A nonsputum blood test capable of predicting progression of healthy individuals to active tuberculosis (TB) before clinical symptoms manifest would allow targeted treatment to curb transmission. We aimed to develop a proteomic biomarker of risk of TB progression for ultimate translation...

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Detaylı Bibliyografya
Yayımlandı:PLoS Med
Asıl Yazarlar: Penn-Nicholson, Adam, Hraha, Thomas, Thompson, Ethan G., Sterling, David, Mbandi, Stanley Kimbung, Wall, Kirsten M., Fisher, Michelle, Suliman, Sara, Shankar, Smitha, Hanekom, Willem A., Janjic, Nebojsa, Hatherill, Mark, Kaufmann, Stefan H. E., Sutherland, Jayne, Walzl, Gerhard, De Groote, Mary Ann, Ochsner, Urs, Zak, Daniel E., Scriba, Thomas J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2019
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6467365/
https://ncbi.nlm.nih.gov/pubmed/30990820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.1002781
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