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A Single Amino Acid Switch Alters the Isoprene Donor Specificity in RiPP Prenyltransferases

Mutation at a single amino acid alters the isoprene donor specificity of prenyltransferases involved in the modification of ribosomally synthesized and post-translationally modified peptides (RiPPs). While most characterized RiPP prenyltransferases carry out the regiospecific transfer of C(5) dimeth...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Am Chem Soc
Prif Awduron: Estrada, Paola, Morita, Maho, Hao, Yue, Schmidt, Eric W., Nair, Satish K.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6467259/
https://ncbi.nlm.nih.gov/pubmed/29924593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.8b05187
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