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Removal of RTF2 from stalled replisomes promotes maintenance of genome integrity
The protection and efficient restart of stalled replication forks is critical for the maintenance of genome integrity. Here we identify a regulatory pathway that promotes stalled forks recovery from replication stress. We show that the mammalian replisome component C20orf43/RTF2 (homologous to S. po...
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| 發表在: | Mol Cell |
|---|---|
| Main Authors: | , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2017
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6467090/ https://ncbi.nlm.nih.gov/pubmed/29290612 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2017.11.035 |
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