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α,γ-Diketocarboxylic Acids and Their Esters Act as Carbonic Anhydrase IX and XII Selective Inhibitors

[Image: see text] Among human carbonic anhydrase (CA) inhibitors, the α,γ-diketocarboxylic acids and esters are still poorly investigated. Here, we report the first compounds of this class (1–6) acting as potent inhibitors at low nanomolar level against the cancer-related human CA IX and XII, and 2–...

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Detaylı Bibliyografya
Yayımlandı:ACS Med Chem Lett
Asıl Yazarlar: Nocentini, Alessio, Lucidi, Alessia, Perut, Francesca, Massa, Annamaria, Tomaselli, Daniela, Gratteri, Paola, Baldini, Nicola, Rotili, Dante, Mai, Antonello, Supuran, Claudiu T.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Chemical Society 2019
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6466837/
https://ncbi.nlm.nih.gov/pubmed/30996814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.9b00023
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