Novel Compounds Targeting the RNA-Binding Protein HuR. Structure-Based Design, Synthesis, and Interaction Studies

[Image: see text] The key role of RNA-binding proteins (RBPs) in regulating post-transcriptional processes and their involvement in several pathologies (i.e., cancer and neurodegeneration) have highlighted their potential as therapeutic targets. In this scenario, Embryonic Lethal Abnormal Vision (EL...

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Argitaratua izan da:ACS Med Chem Lett
Egile Nagusiak: Della Volpe, Serena, Nasti, Rita, Queirolo, Michele, Unver, M. Yagiz, Jumde, Varsha K., Dömling, Alexander, Vasile, Francesca, Potenza, Donatella, Ambrosio, Francesca Alessandra, Costa, Giosué, Alcaro, Stefano, Zucal, Chiara, Provenzani, Alessandro, Di Giacomo, Marcello, Rossi, Daniela, Hirsch, Anna K. H., Collina, Simona
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Chemical Society 2019
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6466816/
https://ncbi.nlm.nih.gov/pubmed/30996806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.8b00600
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