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Autophagy mediates serum starvation-induced quiescence in nucleus pulposus stem cells by the regulation of P27

BACKGROUND: Adult stem cells exist in a quiescent state (G0) within the in vivo niche; the loss of quiescence often leads to a decrease in the number and function of adult stem cells, impairing tissue regeneration and repair. Endogenous repair by nucleus pulposus-derived stem cells has recently show...

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Bibliografiske detaljer
Udgivet i:Stem Cell Res Ther
Main Authors: Li, Bin, Sun, Chao, Sun, Jing, Yang, Ming-hui, Zuo, Rui, Liu, Chang, Lan, Wei-ren, Liu, Ming-han, Huang, Bo, Zhou, Yue
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6466800/
https://ncbi.nlm.nih.gov/pubmed/30987681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-019-1219-8
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