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Impact of NF-κB pathway on the apoptosis-inflammation-autophagy crosstalk in human degenerative nucleus pulposus cells

The NF-κB pathway has been reported to play a very important role in the process of intervertebral disc degeneration (IVDD). Our results demonstrated that knockdown of NF-κB with P65-siRNA can significantly decrease cell apoptosis and the expression of pro-inflammation factors TNF-α and IL-1β in LPS...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Yi, Weiwei, Wen, Yafeng, Tan, Fuqiang, Liu, Xi, Lan, Haiyang, Ye, He, Liu, Bo
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6756901/
https://ncbi.nlm.nih.gov/pubmed/31518335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.102266
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