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Elimination of Wnt Secretion From Stellate Cells Is Dispensable for Zonation and Development of Liver Fibrosis Following Hepatobiliary Injury

Alterations in the Wnt signaling pathway including those impacting hepatic stellate cells (HSCs) have been implicated in liver fibrosis. In the current study, we first examined the expression of Wnt genes in human HSC (HHSCs) after treatment with a profibrogenic factor TGF-β1. Next, we generated HSC...

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Publicado en:Gene Expr
Main Authors: Zhang, Rong, Kikuchi, Alexander T., Nakao, Toshimasa, Russell, Jacquelyn O., Preziosi, Morgan E., Poddar, Minakshi, Singh, Sucha, Bell, Aaron W., England, Steven G., Monga, Satdarshan P.
Formato: Artigo
Idioma:Inglês
Publicado: Cognizant Communication Corporation 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6466178/
https://ncbi.nlm.nih.gov/pubmed/30236172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3727/105221618X15373858350141
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