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Hepatocyte Wnts Are Dispensable During Diethylnitrosamine and Carbon Tetrachloride-Induced Injury and Hepatocellular Cancer

Activation of the Wnt/β-catenin signaling is reported in large subsets of hepatocellular carcinoma (HCC). Upregulation of Wnt genes is one contributing mechanism. In the current study, we sought to address the role of hepatocyte-derived Wnts in a model of hepatic injury, fibrosis, and carcinogenesis...

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Vydáno v:Gene Expr
Hlavní autoři: Preziosi, Morgan, Poddar, Minakshi, Singh, Sucha, Monga, Satdarshan P.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cognizant Communication Corporation 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6190118/
https://ncbi.nlm.nih.gov/pubmed/29519268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3727/105221618X15205148413587
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